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Dr. Christiana (Chris) Bardon

Dr. Christiana (Chris) Bardon

Co-Managing Partner, MPM BioImpact | Physician-Investor in Oncology & Biotech

Dr. Christiana (Chris) Bardon is a physician and investor who serves as co-managing partner of MPM BioImpact, a dedicated biotechnology investment firm active across private and public markets. She is the portfolio manager for the firm’s public-market strategies, BioImpact Equities and the Oncology Impact Funds.

Trained as a physician at Harvard Medical School and the Brigham and Women’s Hospital, Bardon also holds bachelor’s and master’s degrees from MIT and an MBA from Harvard Business School. She began her career as an analyst at MPM, spent years as a healthcare analyst at Fidelity Investments covering biotechnology, life-science tools, and diagnostics, and later founded her own fund before merging it onto the MPM platform roughly a decade ago. She is a trustee of the American Association for Cancer Research Foundation, an executive fellow at Harvard Business School, and a member of the Harvard Medical School Board of Fellows.

Bardon appeared on Open Door Salon alongside Elaine Hamm, president and chief executive of Ascend BioVentures, for a conversation recorded after the J.P. Morgan Healthcare Conference on the state of biotech investing. Speaking from the investor’s seat, Bardon argued that the 2020 financing bubble has largely reset, that capital discipline now separates the companies that survive from those that do not, and that artificial intelligence, while transformative on the services and regulatory side, has not yet meaningfully changed the economics of the clinical-trial process that gates drug approval.

Her advice to founders raising capital was to fix on the single value-creating milestone, proof of concept for a drug, and reach it as efficiently as possible. Above all, she prized intellectual honesty: the managers she backs repeatedly, she said, are the ones who can name their own mistakes without defensiveness and improve their process because of them.

On Open Door Salon

“We Are Trying To Cure Cancer”
Christiana Bardon & Elaine Hamm · January 30, 2026

Episode page & show notes on Open Door Salon

“Focus on what that value-creating milestone is for your therapeutic index or your category, and run like hell without spending too much money along the way.”Christiana Bardon, on Open Door Salon (her advice to founders raising capital)
“When I give my kids $20, they spend $20; I give them $5, they spend $5. They're equally happy. When we have too much money in the sector, like in 2020, we were not capital efficient.”Christiana Bardon, on Open Door Salon (on why scarcity breeds discipline)
“There was some guy discussing bitcoin and another discussing tech, and I said, ‘We're trying to cure cancer.’ And it was like a mic drop. Everyone is touched by cancer. We have the most important and luckiest jobs in the world.”Christiana Bardon, on Open Door Salon (on the meaning of the work)

In this episode

  • After JPM: has the 2020 biotech bubble finally reset?
  • Why too much capital financed too many low-quality companies
  • Down rounds, resets, and the long COVID-era hangover
  • AI's real impact: services and regulatory, not yet the clinic
  • China's rise from CRO to best-in-class drug developer
  • Protecting the NIH-funded talent pipeline
  • Why states can't replace federal research funding
  • Proof of concept: the one milestone that matters
  • Intellectual honesty as the trait she backs repeatedly

Topics

Biotech InvestingOncologyPublic & Private MarketsDrug DevelopmentCapital EfficiencyHealthcare Equity ResearchLife Sciences VCBiotech MarketsAI in Drug DiscoveryCancer

Watch on Open Door Salon

We Are Trying To Cure Cancer | Christiana Bardon & Elaine Hamm

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